Epithalon protocols for sleep typically involve 10mg divided into daily doses (5-10mg total) administered subcutaneously for 10-20 day cycles, repeated 2-4 times per year. Research protocols often use 10mg divided over 5 consecutive days per month for 6 months to achieve sustained pineal gland optimization. Timing should be consistent (evening administration) to support natural circadian rhythms during the treatment period.
PMC: Epithalon dosing protocols