Most peptides have short half-lives and clear within 24-48 hours, so no extensive washout is needed. However, when cycling off GH-releasing peptides, allow 1-2 weeks for pituitary sensitivity to normalize before starting a new protocol. CJC-1295 with DAC requires up to 2 weeks for complete clearance. Research in
Clinical Pharmacokinetics provides peptide-specific half-life data to guide transition timing between protocols.