The most studied ratio is 100mcg CJC-1295 (without DAC) combined with 100-200mcg Ipamorelin, administered 1-3 times daily. This maintains the synergistic GHRH/GHRP balance that produces optimal GH pulse amplitude and frequency. Research from
Journal of Endocrinology demonstrates this ratio maximizes IGF-1 elevation while minimizing desensitization over 3-6 month protocols.